OROTIDINE
- Product Name
- OROTIDINE
- CAS No.
- 314-50-1
- Chemical Name
- OROTIDINE
- Synonyms
- OROTIDINE;Orotidine ,98%;6-Carboxyuridine;URIDIN-6-CARBOXYLIC ACID;URIDINE-6-CARBOXYLIC ACID;orotidine free acid approx. 90%;Orotidine (Uridine-6-carboxylic acid);1,2,3,6-Tetrahydro-2,6-dioxo-3-β-D-ribofuranosyl-4-pyrimidinecarboxylic acid;4-Pyrimidinecarboxylicacid, 1,2,3,6-tetrahydro-2,6-dioxo-3-b-D-ribofuranosyl-;4-Pyrimidinecarboxylic acid, 1,2,3,6-tetrahydro-2,6-dioxo-3-β-D-ribofuranosyl-
- CBNumber
- CB1164936
- Molecular Formula
- C10H12N2O8
- Formula Weight
- 288.21
- MOL File
- 314-50-1.mol
OROTIDINE Property
- Melting point:
- >400 °C
- Density
- 1.847±0.06 g/cm3(Predicted)
- storage temp.
- −20°C
- solubility
- DMSO (Slightly), Methanol (Slightly), Water (Slightly)
- form
- Solid
- pka
- 2.62±0.20(Predicted)
- color
- White to Off-White
Safety
- WGK Germany
- 3
- HS Code
- 29349990
N-Bromosuccinimide Price
- Product number
- O691520
- Product name
- Orotidine
- Packaging
- 1mg
- Price
- $95
- Updated
- 2021/12/16
- Product number
- 296366
- Product name
- Orotidine
- Packaging
- 1mg
- Price
- $531
- Updated
- 2021/12/16
- Product number
- O691520
- Product name
- Orotidine
- Packaging
- 25mg
- Price
- $1620
- Updated
- 2021/12/16
- Product number
- NO08048
- Product name
- Orotidine
- Packaging
- 25mg
- Price
- $1875
- Updated
- 2021/12/16
- Product number
- NO08048
- Product name
- Orotidine
- Packaging
- 0.0025g
- Price
- $90
- Updated
- 2021/12/16
OROTIDINE Chemical Properties,Usage,Production
Uses
Orotidine is a metabolite of Orotic Acid (O691500); a compound used in the preparation of therapeutic agents for chronic obstructive pulmonary disease (COPD) treatment.
Definition
ChEBI: A nucleoside formed by attaching orotic acid to a ribose ring via a beta1N(1)-glycosidic bond.
Enzyme inhibitor
This water-soluble ribonucleoside (FWfree-acid = 288.21 g/mol; CAS 314-50- 1; lmax of 267 nm in 0.1 N HCl (e = 9570 cm–1M–1; another report lists 9800) and 265 nm in 0.1 N methanolic NaOH (e = 8960 cm–1M–1; another report lists 7800)), first observed in Neurospora crassa, is also foound in the urine of cancer patients treated with 6-azauridine, Orotidine is most likely formed from OMP, its 5’-monophosphate ester and the direct precursor of UMP. Orotidine is readily hydrolyzed in dilute mineral acids. Target(s): orotate phosphoribosyltransferase; orotidine-5’-phosphate decarboxylase.